Insulin Term Paper Example | Topics and Well Written Essays - 1750 words

Insulin - Term Paper ExampleThe termination of gluconeogenesis and glycogenolysis results to restitution of normal glucose levels in the blood. The action of insulin in the body is usually brief and the level blood clams changes after the action of insulin subsides. Besides the control of blood sugar, production of insulin initiates a series of metabolic reactions that ar mainly mediated by the changes in expression of over 100 genes in the body (OBrien and Granner, 1117). one and only(a) of the major make of insulin in such physiological processes includes the regulation in the expression of genes that stimulate assimilation of aminic acids, metabolisms of lipids mainly in the muscles and adipose tissue. In addition, insulin affects the expression of genes used for growth, development and survival of incarnate cells (Rhodes and White8)Alfred Sanger did the get-go sequencing of amino acids that make up insulin hormone in 1955 (BCBC 1). According to BCBC (1) insulin is the fir st protein to have its amino acid chain determined and sequenced. Moreover, the hormone is the first peptide protein measured by radioimmunoassay technique. In addition, insulin is the first hormone to be produced in microorganisms using recombinant DNA technology, a process that was successfully conducted in the 1970s. Since then, insulin produced by recombinant DNA technology has been used for treating diabetes, replacing earlier hormones that were produced from purification of insulin from animal species (BCBC1)Disruption of insulin synthesis in the body causes several physiological changes in the body. One of the major impacts of low glucose production is hyperglycemia, a medical checkup condition characterized by an abnormal increase of glucose in the blood plasma (Steiner and James 42). Other effects include poor growth and development of the body. Diabetic patients